Let’s compare some basic numbers (no ascension).

Metric	StS 1	StS 2
Ironclad initial HP	80	80
Ironclad initial gold	99	99
Act 1 count of floors before boss	15	15
Minimum count of rooms on same floor	2	2
Maximum count of rooms on same floor	6	6
Count of guaranteed chest floors	1	1
First fight max total enemy HP*	52	57
First fight min total enemy HP*	30	46
First fight median number of enemies*	1	2
First fight max number of enemies*	2	3
First fight min number of enemies*	1	1
First fight min enemy attack seen, first turn*	0	4
First fight max enemy attack seen, first turn*	13	14
First fight count of distinct fights*	4	4
Min gold earned from first fight*	10	13
Max gold earned from first fight*	18	19
Average gold earned from first fight*	15	17
Potion reward odds on first fight*	50%	50%
Runs where 2+ elite fights are possible*	100%	88%
Runs where 3+ elite fights are possible*	57%	25%
Runs where 4+ elite fights are possible*	0%	0%
Runs where avoiding all elite fights is possible*	100%	100%

*Sampled over roughly 8 runs.

Observations

• The relic that made the enemies of the first three fights 1 HP is no longer available.
• The first fight has much higher odds of having multiple enemies.
• The Spire feels wider in StS 2.

Some other metrics to sample later

• Number of multi-enemy regular fights, by act.
• Number of multi-enemy elite fights, by act.
• Number of multi-enemy boss fights, by act.
• Distribution of room types, by act.
• Uncommon or better card rewards.